Precision genomics involves advances in genetics, data science, clinical biomedicine and biotechnology. Developments in genome sequencing technologies and large-scale biobanking projects are providing opportunities to expand the scope of human genetic diversity in medical genetic studies, and to understand how common and rare variation affects complex traits, disease susceptibility and patient responses to therapy.

In this Cell Symposium, we bring together scientists working to translate human genetic diversity into precise insights regarding the etiology and treatment of major human diseases. This meeting will highlight key themes tied to all sessions: (1) the use of human genomics for precision medicine; (2) the genetic architecture of human health and disease; (3) genomics for underrepresented populations; and (4) technologies and methods for generating and interpreting genomic datasets. We will encourage discussion of these themes in contexts such as cancer, neurogenomics, immunogenomics, and common complex and rare diseases. Through sessions that bring together speakers working on different physiological systems, we aim to discover emerging themes in precision genomics for human health.

Topics of the meeting will include:

• Genetic diversity in human health and disease
• Genomics for underrepresented populations
• Common and rare variation in human disease
• Neurogenomics
• Immunogenomics
• Cancer genomics
• Common complex diseases
• Genomic data science, ethics and privacy
• Technology and methods development