Speaker

Dr. Zhang is a professor in the Medical Research Institute and Frontier Science Center for Immunology and Metabolism at Wuhan University. Her research mainly focuses on developing new CRISPR-Cas tools and applying in primary cells for cell therapy. She has discovered a new Cas9 where editing activity can be robustly regulated by DNA topology (Mol. Cell, 2022) and has developed a robust non-viral DNA delivery method which significant improved CAR-T generation (Nat. Biomed. Engin., 2023). She also developed a base editor based engineering of BCL11A binding motif to treat β-thalassemia (Cell Stem Cell, 2023). Prior to joining Wuhan University, Ying worked in CRISPR Therapeutics as the first scientist where she pioneered the CRIPSR-edited hematopoietic stem cells for treating hemoglobinopathies. She received a Ph.D. in Cell Biology, Stem Cells, and Development from University of Colorado Anschutz Medical Campus. She continued with post-doctoral work in Harvard Medical School.

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