Organizer

Dr. Jonathan (Jony) Kipnis is BJC Investigator and Alan A. and Edith L. Wolff Distinguished Professor at Washington University in St. Louis, where he also directs the Brain Immunology and Glia (BIG) Center.

Dr. Kipnis’s lab studies the interplay between the immune and nervous systems in health and disease. His lab discovered meningeal lymphatic vessels that drain the brain to peripheral lymph nodes, reshaping our understanding of CNS immune privilege. Kipnis lab also identified skull and vertebral bone marrow as local immune reservoirs for the brain and spinal cord. Recent work revealed new brain waste-clearance structures, demonstrated how sleep-driven brain waves drive cerebrospinal fluid flow, introduced engineered T cells as potential therapies for neurodegeneration, and identified endogenous peptides bound to MHCII with immunoregulatory function.

Dr. Kipnis earned his Ph.D. at the Weizmann Institute in Israel, where he was a Sir Charles Clore Scholar and received a prize from the Israeli Parliament (Knesset) for scientific achievements. Among other awards and recognitions, he is a member of the National Academy of Medicine and recipient of the NIH Director’s Pioneer Award.

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