Myeloid cells – mononuclear (monocytes, macrophages, and dendritic cells (DCs)) and polymorphonuclear (neutrophils, eosinophils, basophils, and mast cells), as well as immature myeloid progenitors of both lineages -- play critical roles in immune homeostasis and inflammation. Their dysregulation has been linked to cancer, metabolic, inflammatory diseases, and degenerative diseases, making them increasingly important potential targets for therapeutic intervention.

Together we will discuss areas of long-standing and topical interest in the field of myeloid cell biology, including:

• Ontogeny and basic function

• Resolution of inflammation and cellular cross-talk

• Dysregulation of myeloid cell function in the context of autoimmunity and allergy

• The role of myeloid cells in metabolic disease and the role of intermediary metabolism in myeloid function

• The role of myeloid cells in the control and support of tumorigenesis and tumor growth

We hope to bring together basic scientists, clinicians, and industry to discuss new findings and future challenges in investigating these sentinels of the immune system.