Speaker

Deb Muoio is professor in the Departments of Medicine and Pharmacology & Cancer Biology, George Barth Geller Distinguished Professor of Cardiovascular Disease, and Associate Director at the Duke Molecular Physiology Institute (DMPI) at Duke University. The Muoio laboratory investigates metabolic networks that control muscle and whole-body energy metabolism, with emphasis on mechanisms linking obesity, aging, and physical inactivity to mitochondrial dysfunction and cardiometabolic diseases. During the past 20 years, Dr. Muoio co-led efforts at DMPI to develop and apply mass spectrometry-based metabolomics, proteomics, and metabolic flux analysis for identifying metabolic signatures of health and disease. Her laboratory also developed a sophisticated platform for comprehensive phenotyping of mitochondrial energy transduction. Her team aims to integrate powerful molecular profiling tools with comprehensive respiratory phenomics to identify and understand pathways that connect mitochondrial quality to disease risk.

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