Speaker articles
Take a look at what some of our Metabolites: Organellar communication in health and disease speakers have published recently and chat with them about their work in Sitges, Spain.
Keynote speakers
Nav Chandel, Northwestern University, USA
Mitochondrial integrated stress response controls lung epithelial cell fate
Heather Christofk, University of California, Los Angeles, USA
Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy
ZFP36-mediated mRNA decay regulates metabolism
Speakers
Monther Abu-Remaileh, Stanford University, USA
Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease
The Batten disease gene product CLN5 is the lysosomal bis(monoacylglycero)phosphate synthase
Kivanc Birsoy, The Rockefeller University, USA
Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer
Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
Donita Brady, University of Pennsylvania, USA
BRAFV600E-Driven Lung Adenocarcinoma Requires Copper to Sustain Autophagic Signaling and Processing
The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation
Elvan Boke, Centre for Genomic Regulation (CRG), Spain
Mouse oocytes sequester aggregated proteins in degradative super-organelles
Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I
Lulu Cambronne, University of Texas, USA
SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
Dynamics of SLC25A51 reveal preference for oxidized NAD+ and substrate led transport
Mark Febbraio, Monash University, Australia
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC
Diet-induced gut dysbiosis and inflammation: Key drivers of obesity-driven NASH
Pekka Katajisto, University Helsinki, Finland & Karolinska Institute, Sweden
Cellular shape reinforces niche to stem cell signaling in the small intestine
Metabolic determination of cell fate through selective inheritance of mitochondria
Judith Klumperman, University Medical Center Utrecht, USA
An optimized protocol for immuno-electron microscopy of endogenous LC3
Natalie Krahmer, Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Germany
A spatiotemporal proteomic map of human adipogenesis
EPAC1 enhances brown fat growth and beige adipogenesis
James Olzmann, Berkeley, University of California, USA
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis
Rushika Perera, University of California San Francisco, USA
Autophagy in cancer cell remodeling and quality control
Bao-Liang Song, Wuhan University, China
A sterol analog inhibits hedgehog pathway by blocking cholesterylation of smoothened
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion
Jessica Spinelli, UMass Chan Medical School, USA
Oxygen-Independent Assays to Measure Mitochondrial Function in Mammals
Selenium reduction of ubiquinone via SQOR suppresses ferroptosis
Phillip White, Duke Department of Medicine, USA
BCAA-nitrogen flux in brown fat controls metabolic health independent of thermogenesis
Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion
Roberto Zoncu, Berkeley Research, University of California, USA
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
Antonio Zorzano, IRB Barcelona - Institute for Research in Biomedicine, Spain
TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging
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