Speaker articles
Take a look at what our esteemed speaker have published recently and discuss their research with them in Seattle in November.
Keynotes
Joan Massagué, Memorial Sloan Kettering Cancer Center, USA
Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis
Caroline Robert, Institute Gustave-Roussy, France
Translational control of tumor immune escape via the eIF4F-STAT1-PD-L1 axis in melanoma
Speakers
Eduard Batlle, IRB, Spain
TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
Thomas Brabletz, Friedrich-Alexander University, Germany
Non-redundant functions of EMT transcription factors
Kevin Brindle, Cambridge University, UK
Measurement of Plasma Cell-Free Mitochondrial Tumor DNA Improves Detection of Glioblastoma in Patient-Derived Orthotopic Xenograft Models
Karin de Visser, Netherlands Cancer Institute, The Netherlands
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response
Ayelet Erez, Weizmann Institute, Israel
Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
Tom Gajewski, University of Chicago, USA
WNT/β-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers
Cyrus Ghajar, Fred Hutchinson Cancer Research Center, USA
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy
Philip Greenberg, Fred Hutchinson Cancer Research Center/University of Washington, USA
Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro
Sui Huang, Institute for Systems Biology, USA
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis
David Hyman, Memorial Sloan Kettering Cancer Center, USA
Efficacy of MEK inhibition in patients with histiocytic neoplasms
Charles Mullighan, St. Jude Children’s Hospital, USA
Genomic subtyping and therapeutic targeting of acute erythroleukemia
Kornelia Polyak, Dana-Farber Cancer Institute, USA
TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer
Jeff Rathmell, Vanderbilt University, USA
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
Alice Shaw, Massachusetts General Hospital, USA
Updated Efficacy and Safety Data and Impact of the EML4-ALK Fusion Variant on the Efficacy of Alectinib in Untreated ALK-positive Advanced Non-small-cell Lung Cancer in the Global Phase III ALEX Study
Celeste Simon, University of Pennsylvania, USA
Hif1α Deletion Limits Tissue Regeneration via Aberrant B Cell Accumulation in Experimental Pancreatitis
Matthew Walter, Washington University in St. Louis, USA
Discriminating a common somatic ASXL1 mutation (c.1934dup; p.G646Wfs*12) from artifact in myeloid malignancies using NGS
Zena Werb, University of California San Francisco, USA
Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers
Cathy Wu, Dana-Farber Cancer Institute, USA
Integrative annotation and knowledge discovery of kinase post-translational modifications and cancer-associated mutations through federated protein ontologies and resources
