Speaker

Aye completed her undergraduate studies in Chemistry at Oxford University (2000-2004), and doctoral research in Organic Chemistry with Prof. Dave Evans at Harvard University in 2009. She then switched her research discipline to life science and received her postdoctoral training with Prof. JoAnne Stubbe at MIT. Science in the Aye Lab—established in mid-2012—seeks to understand non-canonical cell signaling processes. Her laboratory is most well-known for investigations into electrophile signaling, a nuanced communication mode whereby on-target engagement between specific reactive metabolites and target proteins, orchestrates precision responses at cellular/organismal levels. Contributions from her laboratory have been recognized globally: recent honors include 2024 Klaus Grohe Prize, 2022 European Research Council grant award, 2021 International Chemical Biology Society Global Lectureship award for distinguished investigators in Chemical Biology, 2021 ACS Arthur Cope Scholar award, 2022 Tetrahedron Young Investigator award in Bioorganic & Medicinal Chemistry, 2020 ACS Eli Lilly award in Biological Chemistry, and 2020 EFMC Young Medicinal Chemist award.

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